CUENCA, Patricia and RAMIREZ, Vanessa. Aberraciones cromosómicas en trabajadoras expuestas a plaguicidas. Rev. biol. trop [online]. , vol, n.3, pp. ABERRACIONES. CROMOSÓMICAS. Dra. Laura Santana Díaz Médico Genetista. Morfología y estructura de los cromosomas humanos. Cariotipo Constitución. PDF | On Jan 1, , Fernado N. Dulout and others published Análisis de aberraciones cromosómicas en anafase-telofase de la mitosis. I. Acción clastogénica.

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Jpn J Cancer Res ; Formation of diastereomeric benzo[a]pyrene diol epoxide-guanine adducts in p53 gene-derived DNA sequences. The micronuclei assay is considered a practical, universally validated and technically feasible protocol which is useful to evaluate the genetic instability induced by genotoxic agents.

The cytogenetic assay cromosojicas a measure of genetic instability induced by genotoxic agents. Fenech M, Morley AA.

The production of micronuclei from chromosome aberrations aberracionee irradiated cultures of human lymphocytes. Sex chromosome loss, micronuclei, sister chromatid exchange and aging: Importance of detecting numerical versus structural chromosome aberrations. Evaluation of micronuclei frequency in the cultured peripheral blood lymphocytes of cancer patients before and after radiation treatment.

Factors contributing to chromosome damage in lymphocytes of cigarette smokers. Cell division, chromosomal damage and micronucleus formation in peripheral lymphocytes of healthy donors: Hainaut P, Pfeifer GP. Fenech M, Crott JW.

Effect of laboratory protocol, scoring criteria, and host factors on the frequency of micronuclei. Norppa H, Falck GC. Sister chromatid exchange and micronucleus frequency in human lymphocytes of 1, subjects in an Italian population: Measurement of micronuclei in lymphocytes.


Effect of smoking habit on the frequency of micronuclei in human lymphocytes: Micronuclei in cytokinesis-blocked lymphocytes as an index of occupational exposure to alkylating cytostatic drugs. Micronucleus induction in gill cells of green-lipped mussels Perna viridis exposed to mixtures of polycyclic aromatic hydrocarbons and chlorinated pesticides. Cancer Lett ; Environ Toxicol Chem ; Clastogenic effect for cigarette smoking but not areca quid chewing as measured by micronuclei in exfoliated buccal mucosal cells.

Influence of smoking habit on the frequency of micronuclei in human lymphocytes by the cytokinesis block method.

Cancer Res ; The micronuclei scoring cromosomcas performed on binucleated cells and the starting sample may vary, although most studies are performed on peripheral blood lymphocytes. High susceptibility to lung cancer analyzed aberrackones terms of combined genotypes of PIA1 and Mu-class glutathione S-transferase genes.

Int J Cancer ; The micronucleus assay in human lymphocytes: Mutat Res ; The cytokinesis-block micronucleus technique: Micronucleus monitoring of a floriculturist population from western Liguria, Italy. The in vitro micronucleus technique. Micronucleus formation in peripheral-blood lymphocytes from smokers and the influence of alcohol- and tea-drinking habits.

Chromosomal instability in amniocytes from fetuses of mothers who smoke.

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The position of the in vitro micronucleus test within the battery crlmosomicas screening for genotoxic potential determination and the regulatory guidelines. Micronuclei in lymphocytes of young patients under antileukemic therapy.

Cytogenetic biomonitoring of Spanish greenhouse workers exposed to pesticides: Micronuclei, nucleoplasmic bridges and nuclear buds induced in folic acid deficient human lymphocytes-evidence for breakage-fusion-bridge cycles in the cytokinesis-block micronucleus assay.


Ginseng reduces the micronuclei yield in lymphocytes after irradiation.

El ensayo de micronúcleos como medida de inestabilidad genética inducida por agentes genotóxicos

Al contrario, varias aberracionse han detectado diferencias entre grupos de fumadores y no fumadores: What do human micronuclei contain? Mutability of p53 hotspot codons to benzo a pyrene diol epoxide BPDE and the frequency of p53 mutations in nontumorous human lung. Environ Mol Mutagen ; Micronuclei frequencies in hospital workers occupationally exposed to low levels of ionizing radiation: A protocol for the in vitro micronucleus test. Contributions to the development of a protocol suitable for regulatory submissions from an examination of 16 chemicals with different mechanisms of action and different levels of activity.

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Micronuclei and chromatid buds are the result of related genotoxic events. Zalacain 1L. Chem Res Toxicol ; Kirsch-Volders M, Fenech M.

Inhibition of oxidative DNA damage, 8-OHdG, and carbonyl contents in smokers treated with antioxidants vitamin E, vitamin C, beta-carotene and red ginseng. The cytogenetic assay for the detection of micronuclei CBMN: