ACIDOS MICOLICOS PDF

Los ácidos micólicos, en específico, poseen funciones biológicas importantes, entre las que se encuentra el papel que desempeñan en la persistencia de la. como los ácidos micólicos, ácido micoserósido, fenoltiocerol, lipoarabinomanano y arabinogalactano contribuyen a la longevidad, a la respuesta inflamatoria. Aunque el análisis de los lípidos de la pared celular (ácidos micólicos) mediante cromatografía líquida de alta presión es una opción Buena y bien conocida, los.

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Triclosan targets lipid synthesis. These provide valuable opportunities for structure- or catalytic mechanism-based design of selective inhibitors as novel anti-TB drugs with improved properties.

Advances in tuberculosis vacine strategies.

Guidebook on molecular modeling in drug design. Does antibody to mycobacterial antigens, including lipoarabinomannan, limit dissemination in childhood tuberculosis? Cepa bacteriana y condiciones de crecimiento.

Evaluation of Mycobacterium smegmatis as a possible surrogate screen for selecting molecules active against multi-drug resistant Mycobacterium tuberculosis. Mainly we identified the presence of phospholipids and micolic acids in the lipid extract showing a high recognition by human gammaglobulin.

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Overexpression of inhA, but not kasAconfers resistance to isoniazid and mcolicos in Mycobacterium smegmatisM. The growing burden of tuberculosis: Chemotherapy of experimental tuberculosis – VI. Targeting tuberculosis and malaria through mocolicos of enoyl reductase: Dot blot de fosfolipidos extraidos de Mycobacterium smegmatis. Surface glycopeptidolipids of M.

Ácido micólico – Wikipedia, a enciclopedia libre

Enoyl reductases as targets for the development of anti-tubercular and anti-malarial agents. Role of a branching mannosyltransferase. Chemoterapy of experimental tuberculosis. Inhibitors of fatty acid synthesis as antimicrobial chemotherapeutics.

Water Res ; Crystal structure and micolicoe of the isoniazid target of Mycobacterium tuberculosis. A mechanism of drug action revealed by structural studies of enoyl reductase.

Rational design of new antituberculosis agents: This paper highlights recent approaches regarding the design of new anti-TB agents, particularly, the enoyl-ACP reductase inhibitors.

Ácido micólico

Discovery of a novel and potent class of FabI-directed antibacterial agents. Isonicotinic acid hydrazide nydrazid and related compounds.

De estudios sobre virulencia hacia herramientas para su control. The envelope of mycobateria.

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Inhibition avidos InhA, the enoyl reductase from Mycobacterium tuberculosisby triclosan and isoniazid. Tal es el caso del estudio desarrollado por Mederos y cols. Mechanism of action of diazaborines. Receptor-independent four-dimensional quantitative structure-activity relationship analysis of a set of isoniazid derivatives.

Lipids of Mycobacterium habana, a synonym of Mycobacterium simiae with vaccine potential.

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The mabA gene from the inhA operon aciods Mycobacterium tuberculosis encodes a 3-ketoacyl reductase that fails to confer isoniazid resistance. Ciudad de la Habana, Cuba. A study of the structure-activity relationship for diazaborine inhibition of Escherichia coli enoyl-acp reductase.