Request PDF on ResearchGate | Dermatitis granulomatosa intersticial con artritis | —Interstitial granulomatous dermatitis with arthritis is a systemic disease. La dermatitis granulomatosa intersticial con artritis es una enfermedad sistémica que afecta a la piel y al sistema musculosquelético. Esta nueva entidad se. Summary. An Orphanet summary for this disease is currently under development. However, other data related to the disease are accessible from the Additional.

Author: Zuk Talar
Country: Brazil
Language: English (Spanish)
Genre: Technology
Published (Last): 20 April 2010
Pages: 206
PDF File Size: 3.81 Mb
ePub File Size: 6.79 Mb
ISBN: 888-9-80648-489-9
Downloads: 44991
Price: Free* [*Free Regsitration Required]
Uploader: Vudok

It presents as annular plaques on the arms, medial thighs and skin folds. Dermis with moderate infiltrate predominantly histiocytic amid gramulomatosa and thickened collagen.

Dermatite intersticial granulomatosa com artrite. Relapsing polychondritis, interstitial granulomatous dermatitis and antiphospholipid syndrome: Topical corticosteroids appear to be only moderately effective, but are still a first line treatment, especially in patients with localized disease. Clin Rheumatol Services on Demand Journal.

Print Send to a friend Export reference Mendeley Statistics. Pemphigus Vegetans in the Inguinal Folds. However, several different types of rash have been inteesticial with the same histological appearance.

There was a problem providing the content you requested

A year-old female presented with recurrent, widespread, erythematous, painful plaques, over a 3-month period. Si continua navegando, consideramos que acepta su uso.

Papules, annular plaques and erythematous-purplish infiltrated nodules on medial surface of left thigh. Its clinical manifestations are variable.

Classically it presents itself as linear subcutaneous cords, known as rope sign. All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License.

Am J Dermatopathol ; 30 2: Altough the original description reported subcutaneous indurated linear cords “the rope sign” along the lateral aspect of the trunk, the clinical picture is now known to be quite heterogeneous, as it may also manifest as patches, papules, nodules or plaques, and at different body sites.


We describe a middle aged woman with rheumatoid arthritis of difficult management and cutaneous lesions compatible with IGDA. Interstitial granulomatous dermatitis was initially described by Ackerman et al in Accentuation of the process in the reticular dermis is a characteristic feature, although abnormalities can involve the full thickness of the dermis or the superficial hypodermis.

We also make a differential diagnosis with interstitial granuloma annulare and discuss the latest articles published in literature.

Differential diagnosis includes other entities related to rheumatoid arthritis, such as rheumatoid nodules, rheumatoid vasculitis, palisaded neutrophilic and granulomatous dermatitis, in addition to rheumatoid neutrophilic dermatosis, which, unlike granulomztosa latter, presents neutrophilic dermal infiltrate and leukocytoclasia without vasculitis under histopathology. She denied any systemic complaints, emergency laboratory tests revealed only microcytic anemia and slightly elevated C-reactive protein and, therefore, she was discharged and prescribed only conservative measures.

Show more Show less. Support Center Dermagitis Center. We report a case of IGD which occurred as the presenting symptom of an underlying autoimmune thyroiditis. Am J Dermatopathol ; 33 8: Interstitial granulomatous dermatitis associated with the use of tumor necrosis factor alpha inhibitors.

Dermatitis granulomatosa intersticial con artritis | Actas Dermo-Sifiliográficas (English Edition)

Rio Branco, 39 Interstitial granulomatous drug reaction is diagnosed by skin biopsy. It has been reported in association with several drugs, lymphoproliferative diseases and autoimmune disorders, such as rheumatoid arthritis, systemic lupus erythematosus and vasculitis, but association with autoimmune thyroiditis is rare.


Interstitial granulomatous dermatitis and paraneoplastic rheumatoid polyarthritis disclosing cancer of the lung. Dense inflammatory infiltrate in interstitial thickened collagen.

Histologically, a diffuse interstitial infiltrate with histiocytes and foci of collagen degeneration is seen, as well as granu,omatosa formation of small granulomas around these areas of degeneration. Dermatitis; Granulomatous disease, chronic; Thyroiditis; Thyroiditis, autoimmune.

March Pages It is histopathologically characterized for affecting all the dermis, differently from IGDA, which is located in the middle and deep dermis and demonstrates an infiltrate rich in neutrophils, with vascular alterations and leukocytoclasia.

Granulomatous dermatitis

Interstitial granulomatous dermatitis with cutaneous cords and arthritis: Clues to diagnosis in dermatopathology. Both forms of granulomatous dermatitis have often arisen in people with other conditions considered autoimmune in origin, implying an immune-complex mechanism may be involved in the pathogenesis. SJR uses a similar algorithm as the Google page rank; it provides a quantitative and qualitative measure of the journal’s impact.

The rash resolves when the responsible drug is withdrawn. Lesions are often tender and may ulcerate. However, despite normalization of thyroid function, there was only transitory improvement of individual lesions, and, after a follow-up of 2 years, new lesions keep on occurring Figure 4. In most cases, this disease is characterized by flares and remissions.

The documents contained in this web site are presented for information purposes only. Prognosis is variable with remissions and exacerbations or spontaneous and complete remission of skin lesions.