Identification of new genovariants of canine distemper virus in dogs from the State of el análisis del gen de la nucleocápside en perros del Estado de México.
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Dog Disorders and Diseases: In the second group, the creation of two sub-groups was observed; one was formed by pathogenic strains from other world regions and the other distenper vaccine strains figure 2. These are some of the reasons why the N gene is a candidate for studies; also the sequences of this gene allow the differentiation een the strains of CDV Simon-Martinez et al The sequences of these genovariants, along with the sequences of other isolates reported worldwide were analyzed in a phylogenetic tree.
This provides a great threat to both the rural and urban communities dn the United States, affecting both shelter and domestic canines. Blood samples of 15 dogs showing clinical signs of canine distemper virus disease, were obtained from veterinary clinics established in Toluca valley; this municipality is located in the central zone of the State of Mexico. The results obtained showed that the N gene sequences belong to seven Canine Distemper Virus genovariants never before reported in the State of Mexico neither in other countries.
With these distances, a phylogenetic tree was constructed using the Neighbor-joining method. For example, all pathogenic strains used in this study have an Aspartic Acid in the amino acidwhile the vaccine strain has an Asparagine. Retrieved from ” https: Other sequences reported worldwide were used too figure sistemper. The data analysis was performed using molecular phylogeny.
Canine distemper – Wikipedia
Bartonella is a type bacteria that can be transmitted to cats, dogs and humans from exposure to infected fleas and…. Molecular analysis of the nucleocapsid protein of recent isolates of canine distemper virus in Japan. Views Read Edit View history. Otros signos adicionales iniciales incluyen:.
In other projects Wikimedia Commons. The results obtained showed that different isolates genetically related are circulating in this region and they are exclusive of Mexico; a similar situation has been previously described for other isolates in other countries Yoshida et alCastilho et ristemper If neurological signs develop, incontinence may ensue.
Vet Microbiol 44, The origin of the word “distemper” is from the Middle English distemperenmeaning to upset the balance of the humors, which is from the Old French destemprermeaning to disturb, which is from the Vulgar Latin distemperare: Trends Microbiol 3, Dogs that have been infected with distemper tend to suffer a progressive deterioration of mental abilities and motor skills.
These signs may or may not be accompanied by anorexiaa runny nose, and discharge from the eye. It is caused by an RNA canine paramyxovirus with an elevated genetic diversity.
Comparison of amino acid sequences. Oxford Living Dictionaries – English.
In other countries, infections of CDV in perroos with history of prior vaccination, involving new variants of the virus have also been observed Mochizuki et alKeawcharoen et al In Greene, Craig E.
J Vet Sci 2, This molecular characteristic among the pathogenic strains and vaccine strains allows the use of this site for the differentiation between pathogenic and vaccinal isolates.
Archived from the original on June 25, This page was last edited on 26 Decemberat These dogs are not protected against the virus, distempef are susceptible to canine distemper infection, continuing the downward spiral that leads to outbreaks throughout the world. CDV has an envelope composed of a membrane protein termed M and two glycoproteins, the hemagglutinin termed H and the fusion protein termed F Mochizuki et al ; the genomic RNA is tightly bound to the nucleocapsid protein, termed N; the major structural protein.
Another contribution of this work is related to the identification of new sequences of the N gene.
Using this genetic information of the CDV, on the one hand, distempfr we can make the molecular diagnosis of CDV, not only identifying positive cases, but also identifying genovariants that cause the disease, because, at least eight genovariants are circulating in Mexico State; new seven genovariants reported here EdoMex-1 to EdoMex-7 and the previously reported CIESAJSMC genovariant Simon-Martinez et al