Dermatol Clin. Jul;11(3) Epidermolysis bullosa acquisita and bullous systemic lupus erythematosus. Diseases of autoimmunity to type VII collagen. Bullous Systemic Lupus Erythematosus (BSLE) is a rare manifestation of . (BP), inflammatory variant of epidermolysis bullosa acquisita (EBA), and linear IgA. However, unlike epidermolysis bullosa acquisita, bullous systemic lupus erythematosus tends to respond dramatically to treatment with.

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Bullous systemic lupus erythematosus with milia and calcinosis. Clin Rheum Dis, 8pp.

J Dermatol, 21pp. Ann Rheum Dis ; Our patient showed only modest improvement on steroids and antimalarials, complete response being seen only with dapsone. Bullous systemic lupus erythematosus with cutaneous mucinosis and leukocytoclastic vasculitis. Derechos de autor Biociencias. Superficial erosions were also noted over the buccal mucosa, hard palate, and lips.

Arch Dermatol,pp. Systemic lupus erythematosus best pract res clin Rheumatol. Sem Cut Med Surg, 17pp.

Bullous Systemic Lupus Erythematosus

Also, the dramatic response to dapsone is highlighted which remains the drug of choice in the management of this disorder. Concurrent painful oral ulcers were reported; though, other mucosae were uninvolved. Lesions are present on covered as well as exposed areas. Other bullous disorders such as bullous pemphigoid, epirdermolysis bullosa acquisita, linear IgA bullous dermatosis and dermatitis herpetiformis has also been reported in association with SLE.


Lupus ampolloso: un verdadero reto diagnóstico y terapéutico | Biociencias

Clin Dermatol, 22pp. National Center for Biotechnology InformationU. Bullous eruption of systemic lupus erythematosus: Clin Exp Dermatol,pp. Diagnostic immunohistochemistry of the skin, pp. This article also discusses the epidemiology, clinical, histopathologic and immunopathologic features, differential diagnosis and the treatment of BSLE. Bullous disease in systemic lupus erythematosus.

Our understanding of the pathology of this interesting and unique dermatologic condition has evolved with improved diagnostic criteria and clinicohistologic profiling. Bullous systemic lupus erythematosus SLE is a clinicopathologically distinctive immunobullous eruption occurring during the course of SLE. Routine histopathology and immunoflorescence studies suggested BSLE and she responded favorably to dapsone.

Occasionally other antigens such as laminin 5, laminin 6, and BP bullous pemphigoid antigen have also been described. J Invest Dermatol, 81pp.

Lupus ampolloso: un verdadero reto diagnóstico y terapéutico

Estelle Hau, MD et al. Efficacy and safety of belimumab in patients with active systemic lupus erythematosus: Int J Dermatol, 33pp. Most reported cases have dramatically responded to dapsone, with cessation of new lesions in days and healing within several days.

Yell JA, Wojnarowska F. The geoepidemiology of systemic lupus erythematosus.


Lupus Eritematoso Sistémico Bulloso en una niña de 10 años de edad. Reporte de un caso

Bulla spread sign and Nikolsky sign were positive. Immunodominant auto-epitopes of type VII collagen are short, paired peptide sequences within the fibronectin type III homology region of the noncollagenous NC1 domain.

Vesiculobullous systemic lupus erythematosus. Over the next 6 months, steroids were completely withdrawn, and dapsone and hydroxychloroquine continued for further 1 year. Bullous eruption of systemic lupus erythematosus.

J Invest Dermatol ; As seen in our case, BSLE developing with or prior to features of SLE can present a diagnostic dilemma; hence, other subepidermal vesicobullous disorders need to be ruled out.

Am J Clin Dermatol ; To improve our lupuw and products, we use “cookies” own or third parties authorized to show advertising related to client preferences through the analyses of navigation customer behavior. William Stohl et al. Camisa, Vesiculobullous systemic lupus erythematosus.

The patient reported three previous, spontaneous abortions, 5months gestation the last one being 6 years back. La respuesta al tratamiento con dapsona fue notable a las 48 horas.